Prooxidant-antioxidant balance in seminal and blood plasma of men with idiopathic infertility and infertile men in combination with rheumatoid arthritis

Background. Male infertility is one of the most serious medical and social problems. Idiopathic accounts for about 30 % cases infertile men. Rheumatoid arthritis associated with a decreased fertility potential. The aim present work was to determine lipid peroxidation level activity antioxidant enzymes such as glutathione peroxidase reductase in seminal plasma blood men idiopathic concomitant autoimmune joint pathology (rheumatoid arthritis). Materials Methods. 45 aged 22–48 were examined. They divided into 2 groups: first group – 23 somatically healthy patients infertility; second 22 rheumatoid arthritis. control consisted 27 males normal semen profile according WHO criteria confirmed parenthood. concentration thiobarbituric acid reactive substance measured plasma. Results. When analyzing fluid, we found that TBARS content 4-fold greater compared fertile (p <0.001), whereas, its within range. activation combination accompanied by statistically significant decrease system. It should be noted more pronounced disorders Conclusions. (1) An increased observed normospermic men, whereas no differences between men; (2) impaired status both (3) showed significantly higher levels infertility, GPx GR groups.